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GH is likely to be involved in the above process simply by its ability to upregulate local IGF production through classical JAK/STAT signaling, but JAK2 can also directly cross phosphorylate IRS1/2 adding another link to the GH-GHR cascade (118, 119)

Lukaszewicz, A., Savatier, P., Cortay, V., Kennedy, H

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They also monitor overall skin health in controlled research settings